Nicotine/Tobacco Research @ CSL

Acute Pharmacokinetic and Pharmacodynamic Effects of “Tobacco-Free” Oral Nicotine Pouches in Smokers

This research is being done to learn more about the short-term effects of oral nicotine pouches, including subjective and cardiovascular effects and also to understand nicotine pharmacokinetics (or how the drug moves through your body) from nicotine pouches in comparison to tobacco cigarettes. Nicotine pouches are becoming more popular and are widely available in retail stores such as tobacco shops and gas stations. However, to date, there has not been much research done to understand the effects of these pouches in tobacco cigarette smokers.

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The purpose of this study is to learn more about the effects of using oral nicotine pouches of different flavors and nicotine strengths in comparison to regular cigarettes. If you are eligible and join this study, you will complete 1 screening visit that lasts about 2 hours and 7 drug administration sessions that each last about 5 hours.

Healthy adults over the age of 21 may join the study. Total possible earnings will be $1030.

If you are interested in this study, please refer to this page.

Oral Cannabidiol for Tobacco Cessation

The purpose of this study is to evaluate the effects of oral cannabidiol (CBD) compared to a placebo on smoking cessation.

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People aged 18-65 years who are current daily tobacco smokers with an interest in quitting may join.  The study will take place on the Johns Hopkins Bayview Medical Center campus at the Johns Hopkins Behavioral Pharmacology Research Unit. If you qualify and choose to take part in this study, compensation of up to $615 can be earned for completing all portions of the study procedures and following all study requirements.

Study Participation consists of:
21 experimental test sessions over the course of 6 weeks. The study will be completed in 3 phases, each lasting two weeks. Study weeks 1, 3, and 5 will be baseline weeks, during which you will smoke cigarettes as you normally would. Study weeks 2, 4, and 6 will be simulated quit attempt weeks, during which you will be asked to attempt to quit smoking cigarettes. You will be at the BPRU for up to 2 hours during each study visit, though most sessions will be about 30 minutes.

If you are interested in this study, please refer to this page.

Cigarette Smoking Decision Study

This research is being done to learn if different types of cigarettes can influence decisions and other types of thinking.

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Healthy men and women who smoke cigarettes and are 18-35 years old are needed to participate in a research study at the Johns Hopkins Bayview Medical Center. This is not a treatment study. The study tests factors that influence smoking behavior. 

Participation involves an initial phone screening and an in person 3 hour screening visit. If qualified, this study requires an additional 9 in person visits lasting approximately 4 hours each. Morning, afternoon, and evening times are available for in-person visits.

You will be paid up to $975 for completing the entire study.

If you are interested in this study, please click this link to see if you are eligible.